Sea como fuere, el tratamiento prolongado con nitratos se suele acompañar de En aquellos pacientes que presentan angina de Prinzmetal sobre un fondo de . We present 2 cases of severe vasospastic angina resistant to intensive medical vagal tone associated with thyrotoxicosis triggers prinzmetal variant angina and Un tratamiento a tener en cuenta en la tirotoxicosis inducida por amiodarona. S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 56, A lead ECG was obtained. From the Cattedra di Fisiopatologia Cardiorespiratoria dell.

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A year-old man was brought to our hospital with acute myocardial infarction and precordial ST elevation. SRJ is a prestige metric based on the idea that not all citations are the same.

Once the diagnosis of hyperthyroidism is established, medical treatment usually suffices, although, in severe cases, most of which are induced by amiodarone, thyroidectomy may be necessary. We present 2 cases of severe vasospastic angina resistant fisiopatolotia intensive medical treatment.

The atenolol that had originally been prescribed was discontinued. These manuscripts contain updated topics with a major clinical or conceptual relevance in modern medicine.

Three months after the fisiopatologix, he was readmitted with unstable angina after detection of transient precordial ST elevation and slight enzymatic elevation. The main characteristic of the initial clinical course was the difficult management, with frequent fissiopatologia episodes, despite the use of high-dose calcium antagonists and nitrates.

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He underwent primary angioplasty with conventional stent implantation in mid ADA. The free thyroxine level was 6.


The present manuscript strengthens the hypothesis concerning causality in the association between hyperthyroidism and vasospastic angina, which, if sufficiently prolonged, can provoke myocardial infarction.

December Next article. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. The cardiovascular effects of hyperthyroidism are well known, and are associated with a hyperadrenergic state and an agonist effect of calcium in the myocardium. A repeated coronary angiography revealed a diffuse, severe spontaneous spasm of anterior descending artery ADA Figure 1which reproduced the admission clinical onset.

The episodes of angina at rest were uncontrollable until diagnosis and proper treatment of the concomitant hyperthyroidism, the onset of which was nearly asymptomatic. Images subject to Copyright. Subscriber If you already have your login data, please click here.

Previous Article Vol Calls from Spain 88 87 40 9 to 18 hours. One year after the initiation of this medication, he was admitted to the hospital with unstable angina, with mild electrical and enzymatic changes. The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles.

Finally, the patient underwent total thyroidectomy, without subsequent recurrence of anginal episodes, even after the calcium antagonists were discontinued 2 months after the surgical procedure. The duration of the follow-up period was 14 months.

Forty-eight hours later, a level of free thyroxine of 4. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. Subscribe to our Newsletter. Fisiopatoologia the management of this entity, it is essential to control the thyroid activity, which can be curative in itself, prinzmmetal the need for subsequent antianginal therapy, 5 especially if there is no accompanying heart disease.

Thyrotoxicosis-Induced Vasospastic Angina

After having experienced several documented episodes of atrial fibrillation and nonsustained ventricular tachycardia, the patient began to receive treatment with amiodarone, in addition to the carvedilol that he was already taking. From Monday to Friday from 9 a. Thus, we highlight the importance of determining thyroid hormone concentrations in cases of vasospastic angina, especially when drug resistance is observed, 4 and even if the signs of hyperthyroidism are mild, 2 a circumstance to which previous treatment with beta-blockers can contribute.


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Thyrotoxicosis-Induced Vasospastic Angina | Revista Española de Cardiología (English Edition)

Si continua navegando, consideramos que acepta su uso. The patient was a year-old man with dilated cardiomyopathy and angiographically normal coronary arteries in 2 prior catheterizations.

Two weeks later, he was readmitted with the same clinical signs and symptoms and the same electrical changes, accompanied by anxiety and resting tremor. This time, coronary angiography revealed diffuse spasm in mid-distal ADA Figure 2which was controlled with intracoronary nitroglycerin.

With a diagnosis of Graves’ disease, the hyperthyroidism was controlled with carbimazole, and the patient has remained asymptomatic after 8 months of follow-up with no need for calcium antagonists, which were discontinued 45 days after he was discharged.

Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. CiteScore measures average citations received per document published. September Pages Iberoamerican Cardiovascular Journals Editors’ Network. Hospital General Universitario de Alicante.

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