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Xerostomia is one of the most a common complication of radiotherapy for head and neck cancers, affecting quality of life. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Parotids, Submandibular glands, Xerostomia, Radiotherapy.
If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. This paper aims to review main studies evaluating tolerance dose of salivary glands.
Access to the PDF text. The present study deals with the morphology of the rat parotid gland and its changes after Trypanosoma cruzi infection. It is suggested that in the infected animals the decrease in body weight could be responsible for retarded sexual maturity, leading to the lower level of testosterone. Parasite Volume 7, Number 2June Current usage metrics About article metrics Return to article.
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Methods of measuring the salivary output are collection of unstimulated glandrs stimulated saliva or 99mTc-pertechnate scintigraphy. Article Abstract PDF 4. Data correspond to usage on the plateform after After 1 8 days of infection with T. Access to the full text of this article requires a subscription. The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Radiothérapie à l’iode 131
Access to the text HTML. Clinical benefit of submandibular gland sparing is more controversial.
Mesure de la fonction salivaire. You can move this window by clicking on the headline. Outline Masquer le plan.
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Moreira 3 and J. A mean dose less than 39 Gy could preserve submandibular gland function. Journal page Archives Contents list. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Several studies demonstrated that late salivary dysfunction after radiotherapy has been correlated to the mean parotid gland dose, with recovery occurring with time. Silva 1J. Benezery aR. The glands of control and infected animals were analyzed by histologic and histoquantitative methods.
In the 45 day infected rats, there was return to the normal pattern.
Services Articles citing this article CrossRef 5. Severe xerostomia could be avoided if at one parotid gland is spared to a mean dose of less than approximately 25—30 Gy. Silva 3A. It can be assumed that decreased levels of epidermal growth factor EGF and neural growth factor NGF caused by the lack of testosterone in infected animals also contribute to the atrophy of the parotid gland and to the proliferation of the connective tissue.
Normal tissue tolerance to external beam radiation therapy: Top of the page – Article Outline. Contact Help Who are we? In addition, these animals displayed an increase in the number of cells undergoing mitosis.